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[9000448.] رقم البحث : 9000448 - |
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The role of microalbuminuria in population screening for chronic kidney disease in an Egyptian village chronic kidney disease in an Egyptian village / |
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قطاع الدراسات الطبية / صحه المجتمع والصحه العامه |
| تخصص البحث : صحه المجتمع والصحه العامه |
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Menoufia Medical Journal / / Vol. 25, No. 2 - July 2012 |
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ربيع الدسوقى البهنســى |
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chronic kidney disease, diabetes mellitus, early detection, hypertension,
microalbuminuria, prevalence, screening |
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Objectives
The study aimed at determining the prevalence of and risk factors for chronic kidney
disease (CKD) using microalbuminuria (MA) as a screening test in a rural area in
Gharbia Governorate.
Background
CKD is being increasingly recognized as a public health problem. There is still paucity
of data on the prevalence of and risk factors for CKD by using MA as a screening test
in the Middle East.
Methods
A randomly chosen sample of 320 apparently healthy individuals were interviewed in
Shennera village in Gharbia Governorate using a structured questionnaire including
information about risk factors for MA. They were also subjected to laboratory
investigations including analyses of microalbumin, creatinine, and random blood sugar
levels and lipid profile.
Results
The mean age of the studied sample was 35.7± 13.7 years; 50.9% were male.
Only 85% of the sample had sufficient income. The prevalence of MA was 14.4%.
The prevalence of CKD (estimated glomerular filtration rateo60 ml/min/1.73m2+ MA)
was 15.6%, but those with elevated creatinine levels comprised 2.8% of the studied
group. MA showed an increasing trend with age. The prevalence of MA was
significantly higher among diabetic patients, hypertensive patients, obese individuals,
cardiovascular disease patients, and smokers. The independent predictor variables
associated with the presence of MA in a mutually adjusted logistic regression
model were diabetes (odds ratio = 8.62, 95% confidence interval: 2.62–28.31)
and hypertension (odds ratio= 4.92, 95% confidence interval: 1.63–14.86).
Conclusion
Screening of MA seemed to be an easy, equally, or even more efficient method for
early identification of significant numbers of individuals with CKD compared with other
conventional methods, particularly among those with uncontrolled or undetected
diseases such as diabetes or hypertension. |
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