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[9002234.] رقم البحث : 9002234 - |
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MDCT combined parameters in characterization of adrenal masses in cancer patients; A prospective study in South Egypt Cancer Institute / |
| تخصص البحث : General |
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SECI Oncology Journal / / vol.6 - 2018 |
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ساره محمد عباس عبد الحفيظ |
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ولاء طلعت كامل محمد شعيب - مؤلف رئيسي |
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Adrenal adenoma, histogram analysis, absolute percentage washout, relative percentage washout. |
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Abstract Objective: to evaluate the role of combined MDCT parameters in distinguishing benign from malignant adrenal masses in well known oncological patients. Methods: CT protocol included pre-contrast scan, venous and delayed contrast-enhanced scans assessing the mass size, pre contrast attenuation, histogram & post contrast absolute and relative percentage washout .Statistical analysis of the data was done. Results: The study included 40 patients with 44 adrenal masses. Adrenal masses included 7 lipid rich, 6 lipid poor adenomas, 7 neuroblastomas and 24 metastases. Combined CT parameters including the size (2.25 cm as cut off value), pre contrast attenuation value (<10 HU as cut off value), the 10% negative pixels mean attenuation threshold value for unenhanced CT scan, post contrast absolute percentage washout of 60% and relative percentage washout at 15 min delay were calculated, they yielded a valuable diagnostic protocol with an accuracy of 91.3 %, sensitivity of 100% and specificity of 93.55% for distinguishing the nature of adrenal masses. Conclusion: Combining the studied CT parameters yielded a powerful diagnostic protocol in distinguishing benign from malignant adrenal masses. |
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