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SECI Oncology Journal /
 SECI Oncology Journal /
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[9002234.] رقم البحث : 9002234 -
MDCT combined parameters in characterization of adrenal masses in cancer patients; A prospective study in South Egypt Cancer Institute /
تخصص البحث : General
  SECI Oncology Journal / / vol.6 - 2018
  ساره محمد عباس عبد الحفيظ
  ولاء طلعت كامل محمد شعيب - مؤلف رئيسي
  Adrenal adenoma, histogram analysis, absolute percentage washout, relative
percentage washout.
  Abstract
Objective:
to evaluate the role of combined MDCT parameters in distinguishing benign from malignant
adrenal masses in well known oncological patients.
Methods:
CT protocol included pre-contrast scan, venous and delayed contrast-enhanced scans
assessing the mass size, pre contrast attenuation, histogram & post contrast absolute and
relative percentage washout .Statistical analysis of the data was done.
Results:
The study included 40 patients with 44 adrenal masses. Adrenal masses included 7 lipid rich,
6 lipid poor adenomas, 7 neuroblastomas and 24 metastases. Combined CT parameters
including the size (2.25 cm as cut off value), pre contrast attenuation value (<10 HU as cut off
value), the 10% negative pixels mean attenuation threshold value for unenhanced CT scan,
post contrast absolute percentage washout of 60% and relative percentage washout at 15 min
delay were calculated, they yielded a valuable diagnostic protocol with an accuracy of 91.3 %,
sensitivity of 100% and specificity of 93.55% for distinguishing the nature of adrenal masses.
Conclusion:
Combining the studied CT parameters yielded a powerful diagnostic protocol in
distinguishing benign from malignant adrenal masses.
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