Search In this Thesis
   Search In this Thesis  
العنوان
Assessment of Mother-to-Child transmission of Hepatitis C Virus in Egyptian Pregnant Women /
المؤلف
Mohammed, Belal Khaled Abd El-Monem.
هيئة الاعداد
باحث / Belal Khaled Abd El-Monem Mohammed
مشرف / Manal Hamdy El-Sayed
مشرف / Fatma Soliman Elsayed Ebeid
مناقش / Aya Mostafa Kamal El-Din
تاريخ النشر
2019.
عدد الصفحات
117p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - طب اطفال
الفهرس
Only 14 pages are availabe for public view

from 117

from 117

Abstract

A vertically transmitted infection is an infection caused by pathogens (such as bacteria and viruses) that uses mother-to-child transmission, that is, transmission directly from the mother to an embryo, fetus, or baby during pregnancy or childbirth. It can occur when the mother gets an infection as an inter-current disease in pregnancy.
The current study was conducted to six thousand and seven hundred and thirty four (6734) women delivered in El Demerdash Maternity Hospital in the period from January 2018 till June 2018.
Collection of detailed data from Patients files and divided them into non screened and screened by antibodies and who do PCR for HCV and data of their neonatal outcome
Demographic characteristics and risk factors for HCV among the studied pregnant women (6734 pregnant women) show that less than two thirds of pregnant women were multiparous (4244 pregnant women = 63%), about one third had previous CS (2300=34.2%), less than tenth of pregnant women (629=9.3%) had previous abortion and about two percent of pregnant women had previous hospitalization, operation or blood transfusion (451=6.7%).
Labor characteristics of the studied pregnant women show that less than half of the studied pregnant women underwent CS (2973 pregnant women =44.1%).
Neonatal outcome of the studied pregnant women include sex, weight, APGAR score, gestational age, IUGR or not and if need NICU admission or not.
Comparison according to screening status regarding neonatal outcome of the studied pregnant women show that no significant difference between screened and non-screened pregnant women regarding neonatal outcome.
Comparison according to HCV infection regarding neonatal outcome show that no significant difference between pregnant women with and without positive HCV.
HCV screening among the studied pregnant women show that less than one third of pregnant women underwent screening for HCV.
Our study show that the screening findings among the studied pregnant women show that about 0.1% of the screened pregnant women was positive for HCV.
Comparison according to screening status regarding demographic characteristics and risk factors show that no significant difference between screened and non-screened pregnant women regarding demographic characteristics and risk factors
Comparison according to screening status regarding laboratory findings show that no significant difference between screened and non-screened pregnant women regarding Laboratory findings.
Comparison according to screening status regarding labor characteristics show that no significant difference between screened and non-screened pregnant women regarding Labor characteristics.
Comparison according to HCV infection regarding demographic characteristics and risk factors for HCV show that pregnant women with HCV-positive had significantly older age and more frequent mutliparity as well as previous CS, abortion, hospitalization, operation and blood transfusion, and had significantly lower hemoglobin and had significantly more frequent CS.
Logistic regression for risk factors for HCV Ab among the studied pregnant women shows that only previous hospitalization and previous transfusion were significant risk factors for positive HCV Ab