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العنوان
ENVIRONMENTAL RISK FACTORS FOR CHILDHOOD ASTHMA INTERVENTIONAL EFFECT OF ERADICATING INDOOR ALLERGENS /
المؤلف
El Shourbagy, Mahmoud Awad El sayed.
هيئة الاعداد
باحث / Mahmoud Awad El sayed El Shourbagy
مشرف / Mahmoud Serry Al-Bukhari
مشرف / Howayda Mohamed Kamal
مناقش / Ahmed Esmat Shoman
تاريخ النشر
2014.
عدد الصفحات
232 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة عين شمس - معهد البيئة - قسم العلوم الطبية الاساسية
الفهرس
Only 14 pages are availabe for public view

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from 232

Abstract

Children with asthma are exposed to multiple indoor allergens in their homes and many environmental risk factors that induce asthma symptoms. Reductions in these asthma triggers have been difficult to achieve and remediation intervention for single allergen have seldom been associated with decreased morbidity from asthma. The objective of this study was to determine whether a collaborative reduction for multiple asthma triggers present in indoor environmental could improve asthma related outcomes using environmental intervention for indoor allergens.
One hundred children with atopic asthma (age range 5-11 years), were enrolled in a controlled trial of an environmental intervention that lasted for six months and included education and remediation for exposure to multiple allergens. Home environmental exposures and asthma related complications were assessed six months after effective intervention; Children were randomly divided into two groups, an intervention group and a control group. The intervention group had fewer days with symptoms than did the control group during the intervention period (P<0.001) with a significant decline in admissions to emergency departments, hospitalization as well as decline in level of home allergens as D.Pteronyssinus and reduced complications of asthma. In conclusion, reducing exposure to indoor allergens significantly enhances quality of life for childhood asthma, as well as decreasing asthma symptoms.
Childhood asthmatics are commonly exposed to multiple allergens which may contribute to the increased asthma-related complications. Asthma management guidelines have stressed the need for environmental control measures but there is limited evidence of their efficacy (NHLB, 1997). Previous studies of environmental interventions for patients with asthma
have focused on single allergens such as dust mites rather than on multiple exposures encountered in many patients with childhood asthma. Measures to avoid exposure to dust mites , including bedding encasement, have reduced the levels of exposure to these allergens, but their clinical effectiveness remains a maker of controversy, (carter MC et al,2001).Exposure to cockroach allergens may aggravate asthma but reducing allergens levels has had no apparent clinical benefit.