الفهرس | Only 14 pages are availabe for public view |
Abstract Colorectal cancer is the most common GIT malignancy all over the world with a mortality rate of 3,9%. Over one-half of the patients who die of colorectal cancer have liver metastases at autopsy , and the majority of these patients die as a result of liver metastases. The majority of patients with hepatic metastases are not suitable for resection although the resection is the best way of survival for a patient suffers from hepatic metastases from colorectal cancer. So patients who may benefit from this procedure must be chosen carefully according to specific criteria. They undergoes some non invasive imaging modalities like computed tomography, positron emission tomography using florine-18 labelled flurodeoxy-glucose and they receive neoadjuvant ,adjuvant chemotherapy to improve the results of the procedure. Patients considered not suitable for the resection according to number or distribution of liver metastases, undergo systemic chemotherapy , and some other new therapies such as portal vein embolization ,radiofrequency ablation and cryosurgery. Summary - 164 - In conclusion , surgery is the most effective form of therapy for CRLM .Recent advances in imaging modalities have helped in better patients selection for surgery .Newer chemotherapeutic agents and surgical and radiological interventions have meant that an increasing number of patients can now be considered suitable for surgical resection |