الفهرس 
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Abstract
The present study was carried out at the laboratory of fish nutrition, Faculty of Fish Resources, Suez University. Results obtained from the present study could be summarized as follows:
Using solid-state fermentation (SSF) with Bacillus subtilis ATCC35854 significantly (P<0.05) increased dry matter, crude protein, lipid and ash contents of soybean meal. Moreover, SSF with Bacillus subtilis significantly decreased fiber content of fermented soybean meal (FSBM).
The first experiment started on 1 September 2015 and termenated on 7 December 2015 (98days). The highest BW, WG and SGR were recorded by fish fed the diet (Control diet, D-33 fish meal replaced with FSBM,) with insignificant differences between the two groups.
The best feed conversion ratio (FCR), the highest protein efficiency ratio (PER) and protein productive value (PPV) recorded by fish fed diets Control diet, D-33. The total replacement of FM with 100 SBM led to a significantly (P<0.05) poor FCR ratio and lower PER (P<0.05) compared with the other experimental diets.
There were insignificant differences in body crude protein, crude lipid and ash content of fish fed the experimental diets (P>0.05). Body protein content tended to decrease as the level of fish meal protein replacement increased from 0 to 100%, while, body lipid had the opposite trend.
No significant (P>0.05) difference was found in hematocrit (Htc), hemoglobin (Hb) , red blood cells (RBCs) and White blood cells (WBCs), among fish treated with all tested diets.
The different in histological section of liver showed in fatty liver and it shows in D-100SBM (100% replaced fish meal with soybean meal).
The different in histological section of intestine showed presence of villi, goblet cell and thickness of epithelium cell and the optimum histological section for intestine showed in control diet and in D-33 FSBM (33% fish meal replaced with fermented soybean meal).
The second experiment started 1 October 2015 and termanated on 6 January 2016 (98days). The highest BW, WG and SGR were recorded by fish fed the diet (Fish meal diet and fermented diet with corn gluten and methionine,) with insignificant differences between the two groups.
The best feed conversion ratio (FCR), the highest protein efficiency ratio (PER) and protein productive value (PPV) recorded by fish were fed fish meal diet and fermented diet with corn gluten and methionine. The total replacement of FM with 100 FSBM (100% fermented soybean protein) led to a significantly (P<0.05) poor FCR ratio and lower PER (P<0.05) compared with the other experimental diets.
There were insignificant differences in body crude protein, crude lipid and ash content of fish fed the experimental diets (P>0.05). the highest body protein content recorded in (Fish meal diet and fermented diet with corn gluten and methionine).
No significant (P>0.05) difference was found in hematocrit (Htc), hemoglobin (Hb) , red blood cells (RBCs) and White blood cells (WBCs) among fish treated with all tested diets.
The different in histological section of liver showed in fatty liver and it shows in D-100 fish meal replaced with soybean meal. And the different in histological section of intestine showed presence of villi, goblet cell and thickness of epithelium cell and the optimum histological section for intestine showed (Fish meal diet and fermented diet with corn gluten and methionine).
The present study concluded that:
• The nutritional value of soybean could be improved by the solid-state fermentation with Bacillus subtilis, as it increases the protein content and decrease fiber content.
• Fishmeal could be replaced by fermented soybean meal at level 33% without any significant effect on growth indices, feed utilization, blood properties and histological section of Nile tilapia (Oreochromis niloticus) fingerlings.
• Fish meal free diet content of fermented soybean meal with corn gluten and methionine can give the same effect of fish meal diet on growth indices, feed utilization, blood properties and histological section for Nile tilapia (Oreochromis niloticus) fingerlings.