الفهرس 
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Abstract
The link between non-communicable diseases and infectious
agents continues to expand . Helicobacter Pylori which is a chronic
bacterial infection of the stomach that is usually acquired in childhood
can cause gastritis, gastric cancer and peptic ulcer disease.
Recently, a new relation between Helicobacter Pylori infection
and coronary heart disease was raised . Our study is a trial to find out
any association between Helicobacter Pylori infection and coronary
heart disease .
A total of fifty subjects were included in this study, forty of them
were patients of coronary heart diseases taken as a study group and
the remaining ten healthy persons as a control group. The study group
was divided into two subgroups: subgroup A comprised thirty patients
with myocardial infarction followed by angina and subgroup B
which included ten patients suffered from angina only.
All of the patients with coronary heart disease are non-smokers
and none of them had known risk factors as diabetes mellitus, hypertension,
hyperlipidaemia and hyperuricaemia .
Laboratory investigations, electrocardiographic studies, serological
examination for detection of Helicobacter Pylori infection and upper
endoscopy followed by gastric biopsy taking from the seropositive
cases were performed .
- lID-
Serological examination of the study group revealed that thirty of
the forty patients with coronary heart disease (75%) showed positive
serologic test for Helicobacter Pylori infection compared to (40%) of
the control cases .
The percentage of Helicobacter Pylori infection in the infarction
subgroup was (76.6%) and it was (70%) in the angina subgroup.
Helicobacter Pylori infection in the males of the study group was
(76.5%) while it was (66.67%) in the females. A percentage of
(53.8%) of the infected males were suffering from moderate infection
(grade 2 gastritis) while (46.2%) showed severe infection (grade 3
gastritis) , on the other hand (50%) of the infected females suffered
moderate infection and the other (50%) showed severe infection.
A percentage of (46.67%) of the infected patients with coronary
heart disease showed severe infection with Helicobacter Pylori while
(53.33%) showed moderate infection. All cases with severe infection
were suffering from myocardial infarction while the cases presented
with angina only suffered from moderate infection.
We found statistical significance in the percentage of Helicobacter
Pylori infection between the study and the control group and also in
the severity of Helicobacter Pylori infection between infarction and
angina subgroups.
On the other hand, there was no statistical difference in the
percentage of infection between infarction and angina subgroups,
moreover, no observed statistical significance in the percentage of
Helicobacter Pylori infection between males and females in the study
group.
It could be concluded that Helicobacter Pylori infection should be
put as a risk factor for the development of coronary heart disease and
should be energitically eradicated by proper antibiotic therapy.
However , a future work should be planned to clarify the pathogenesis
of increased incidence of coronary heart disease in patients
with Helicobacter Pylori infection.