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العنوان
Study of Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery/
المؤلف
Ghali, John Adel Zaki.
هيئة الاعداد
باحث / جون عادل زكى غالى
مشرف / شريف سيد علي سلطان
مشرف / احمد محمد محمود خميس
مشرف / فؤاد فاروق محمد جدوع
تاريخ النشر
2024.
عدد الصفحات
109P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2024
مكان الإجازة
جامعة عين شمس - كلية الطب - التخدير
الفهرس
Only 14 pages are availabe for public view

from 109

from 109

Abstract

SUMMARY AND CONCLUSION
D
elayed recovery from anesthesia remains one of the biggest challenging events that involve the anesthesiologist.. The time to emerge from anesthesia is affected by patient factors, anesthetic factors, duration of surgery, and painful stimulation. The principal factors responsible for delayed recovery following anesthesia are anesthetic agents and medications used in the perioperative period. Nonpharmacological causes may have a serious role, hence recognizing these conditions is important. Enhancement of post anesthesia recovery is now becoming an important goal. Different tools of assessment of recovery and drugs proposed to enhance it are increasingly being tried and assessed.
Modafinil is a wakefulness-inducing compound prescribed for treatment of excessive daytime sleepiness because of sleep disturbances such as OSA or narcolepsy and also used in the management of fatigue associated with different conditions including depression, cancer, or tiredness in military personnel. Modafinil was tried in our study in comparison to placebo to show the impact of our drug on post anesthesia recovery.
This study was designed to study effects of preoperative Modafinil on recovery profile of morbidly obese patients scheduled for bariatric surgery.
It was conducted to 20 patients of both sexes, scheduled for bariatric surgeries. Cases were aged 18-60 years, ASA physical status ІІ or III with BMI 40-50 kg/m2.
The patients were randomized by computer software randomization and divided into two equal groups; group modafinil (n =10 patients) that received oral 200 mg modafinil 8 hours before surgery and then another 200 mg 2 hours before surgery and group placebo (n =10 patients) that received placebo through the same regimen as modafinil.
The following parameters were assessed and recorded; immediate recovery times, assessment of cognitive recovery, assessment of emotional (general) status and Modified Aldrete Score.
In Conclusion: Modafinil significantly shortened immediate post anesthesia recovery times when compared to placebo, however our results didn’t show statistically significant differences between modafinil and placebo groups regarding cognitive recovery, emotional (general) status and Modified Aldrete Score.