الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Cardiomyopathy are disease of the heart muscle, portrayed by abnormality in chamber span also wall thickness, or utilitarian contractile dysfunctions mostly systolic alternately diastolic dysfunction in the non-attendance for coronary vein disease, hypertension, valvular disease, alternately intrinsic coronary illness. With a poor prognosis highly mortality. The incidence rate is 0.57 cases per 100,000 children.
Cardiomyopathy can be classified into five clinical phenotypes: hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), restrictive cardiomyopathy (RCM), left ventricular non-compaction cardiomyopathy (LVNC) and arrhythmogenic right ventricular cardiomyopathy (ARVC).
Several types of medications are used in children with DCM to treat heart failure symptoms and to stop the heart from deterioration. Common medications include angiotensin-converting enzyme (ACE) inhibitors (captopril, enalapril and lisnopril), to relax arteries and decrease the heart’s workload and diuretics (frusemide, spironolactone) to reduce excess fluids in the lungs or other organs, and digoxin to improve the heart’s ability to pump blood through the body.
MMP-9 need been restricted inside the cardiomyocyte also might straight forwardly harm those contractile mechanical assembly by cleavage of the myosin heavy chain. Moreover, both myocardial and plasma levels of MMP-9 have been reliably discovered will be raised on patients with. dilated cardiomyopathy.
We performed a study to asses the relationship between serum matrix metalloprotinases-9 (MMP-9) and left ventricular functions in children with DCM.