الفهرس 
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Abstract
This work was conducted to identify and characterize RHDV in naturally and
experimentally infected rabbits, tracing the histopathological changes in
different organs and to evaluate the genetic diversity of RHDV circulate in
different Egyptian provinces. Moreover, to determine the genetic relationship
among such isolates at the molecular level during the period from January 2019
to May 2022.Ninteen suspected liver samples were collected from outbreaks
that occurred in 9 provinces during 2019 and 2022. Ten liver samples out of 19
are positive with slide and plate HA test. HA titer ranged from 5 log 2 to 12 log
2. Positive liver homogenates are confirmed to RHDV with RT-PCR and
histopathology. Further characterisation of selected 4 viral strains was
performed by nucleotide sequencing of VP60 gene. Based on nucleotide
sequence analysis, 3 isolates were identified as RHDV var2 strains, while one
isolate was assigned as classical strain.