الفهرس 
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Abstract
Salmonella is one of the most common food poisoning microorganisms that cause different diseases in chickens leading to the decreased growth rate of chickens, decreased egg production, and maybe the death of chickens so it causes high economic losses, as well as Salmonellosis is considered one of the high dangerous zoonotic diseases that threaten the human health so recently it is very important to study the chickens immune response against Salmonella infection as chickens are the most reservoir of the Salmonella, searching how to stimulate the chick immune response and find new ways for minimizing chicken infection, in turn, to decrease the economic losses as possible and to cut the food chain cycle avoiding human infection.
Therefore, the aim of this study was to investigate the Salmonella occurrence in chickens, in addition to the immune response of one-day-old broiler chicks, Ross 308, against in-vivo Salmonella typhimurium infection, was also assessed through the evaluation of heterophile phagocytosis and mRNA expression of a selected set of cytokines, IgA and other regulating immune genes in the cecum and spleen, representing their mucosal and systemic responses, respectively.