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العنوان
The role of methylene blue spray to keep parathyroid gland and recurrent laryngeal nerve safe during thyroidectomy \
المؤلف
Hermina, Joseph Ellia Fahmy.
هيئة الاعداد
باحث / جوزيف ايليا فهمي هرمينا
مشرف / أحمد محمد كمال أحمد
مشرف / رامي ميخائيل نجيب
مشرف / ايمن مجدي بطرس
تاريخ النشر
2024.
عدد الصفحات
190 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
جراحة
تاريخ الإجازة
1/1/2024
مكان الإجازة
جامعة عين شمس - كلية الطب - الجراحة العامة
الفهرس
Only 14 pages are availabe for public view

from 190

from 190

Abstract

Problems of thyroid organ comprise second most normal endocrine sickness following diabetes mellitus with expanding quantities of entanglements and signs to thyroid medical procedures. Difficulties of thyroid medical procedure were straightforwardly connected to degree of resection and conversely corresponding to experience of working specialist. At point when activity was acted in particular communities, it was protected with low bleakness and a practically 0% mortality.
The really postoperative inconveniences of TD were intermittent LN (RLN) paralysis and hypoparathyroidism, and post-employable hypoparathyroidism is most often experienced difficulty after TD that prompts hypocalcemia. Hypoparathyroidism after TD was made by direct injury parathyroid organ or injury for its blood supplies, that prompts post-employable hypocalcemia which influences physical and mental wellbeing of patient and protracts medical clinic stay. patients likewise bear extra monetary weights when they experience these inconvenience, including medical clinic charges to examinations, lab testing, and expanded length of emergency clinic stay.
Hypocalcemia can be available with peri-oral deadness, deadness of fingertips and positive of Chvostek’s sign. their might be muscle fits, squeezing, seizures, or cardiovascular arrhythmia in extreme cases. Treatment of hypocalcemia comprises of giving patients calcium enhancements and vitamin D, So keeping away from parathyroid organ injury during TD means a lot for think often about it.
Injury to RLN brings about a frail voice or loss of voice and yearning, and two-sided nerve injury prompts dyspnea and frequently dangerous glottal block. In these way, Distinguishing RLN and para thyroid organ was a daily practice to all thyroid and parathyroid medical procedures and guaranteeing nerve integrity was suggested.
MB, which was a drug and color that had been utilized over a long period, was protected and promptly accessible. It tends for be in shower structure and it isn’t costly, additionally, it was arranged effectively in Ain Jokes College Clinic labs. It was filled in a clean moved shower bottle in 100ml 70% liquor. In wake of utilizing these shower intra-employable we found which MB splash on careful field is consumed by parathyroid organ quicker than in encompassing peri-thyroidal region. So it was delicate for parathyroid organ and can indicate it in view of quick assimilation and wash out of color by organ quicker than different tissues. Additionally we can distinguish RLN intraoperatively as a flawless construction in tracheoesophageal groove. So we can distinguish RLN and parathyroid organ utilizing MB shower. We did a forthcoming companion study with similar between two gatherings of patients, one gathering laid out with customary procedure of TD while other gathering laid out utilizing MB shower for see that bunch with less post-usable hypocalcemia and RLN injury. Sixty patients with harmless and threatening goiter problems went through TD doled out into two gatherings: bunch 1 (control bunch) included 30 cases laid out with ordinary strategy and gathering 2 (interventional bunch) included 30 cases worked upon with MB splashing method. All patients did pre-employable examinations and agreed for take an interest. Additionally, post-employable examinations and follow up are proposed for all patients especially individuals who created hypoparathyroidism and observing of calcium level is finished until serum calcium level got back for business as usual.
Intra-usable (bunch 2) we saw that waste of time season of parathyroid organs is 4 for 7 min yet to thyroid organs it is range 15 for 25 min. intermittent LN (RLN) nearly didn’t accept stain by any means as wash-out time 0.1 min. What’s more, we applied a little very much assessed histopathological test from little part that got waste of time of color first for demonstrate that is a parathyroid tissue. Care is taken for stay away from injury of para-thyroid organs and intermittent LN up and down its course. outcomes showed which in bunch 2; 28 patients have ordinary Ca++ level (93.3%) while 2 cases have low Ca++ level (hypocalcemia) (6.7%). However, in bunch 1; 22 patients have ordinary Ca++ level (73.3%) while eight cases have low Ca++ level (hypocalcemia) (26.7%). two patients in bunch 2 and 8 patients in bunch 1 who created hypocalcemia are made do with IV and oral supplementation of calcium and vitamin D and recuperation happened inside a time of multi week for multi month. Additionally, all patients in review have free versatile vocal lines by preoperative vocal rope assessment then one case created postoperative transient two-sided vocal string loss of motion in bunch 1 and no vocal line love is seen in bunch 2.
The two gatherings thyroid last pathology is variety of begnin goiter and dangerous and little very much assessed histopathological tests taken in bunch 2 showed; 18 of cases (60%) affirmed as parathyroid tissue while 12 of cases (40%) not affirmed. Those 12 cases that not affirmed as parathyroid tissue shows; 10 cases are greasy tissue (83.3%) while 2 cases are lymph hubs (LN) (16.7%).
So ongoing review demonstrated which we can distinguish parathyroid organs as well as repetitive LNs utilizing MB shower in safe manner. Furthermore, it was more secure than intravascular methods that guarantee just parathyroid organ representation with a ton of entanglements so not utilized any longer. that assisted us with getting less hypocalcemia post-employable and RLN wounds. Likewise, ongoing review includes no extra expense patient as color was modest and we utilized no costly gadget. Just color and our vision are utilized.