الفهرس 
Sepsis OverviewOnly 14 pages are availabe for public view
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Abstract
Sepsis is a life-threatening organ dysfunction caused by a deregulated host response to infection. Survival benefit has been linked to prompt identification of sepsis and septic shock and early administration of antimicrobials. This pathway incorporated bundles of care that included taking blood cultures, antibiotic administration within an hour of triage and fluid resuscitation. This program aimed to reduce preventable harm to patients through improving the recognition and management of sepsis. The aim of this study is to determine the predictive performance of qSOFA, and SIRS scores for adverse outcomes of patients presenting to emergency department of Menoufia University Hospitals with suspected infection. Patients & Methods: This was a comparative study performed & was conducted to 60 patients presented to emergency department Patients were divided into 2 groups: group A (30 patients) was evaluated according to SIRS score & group B (30 patients) was evaluated according to qSOFA score All the patients were subjected to history taking, measurement of the patient’s hemodynamic parameters by ABCDE assessment and investigations (CBC, coagulation profile, LFTs, KFTs, lactic acid level, urine analysis, blood cultures and arterial Blood gases) and radiological tests (abdominal US and computed tomography (CT) scans) Then the outcomes of each patient were recorded in the form of ward admission, ICU admission, mortality, operative and outpatient The current study shows the age of group A ranged from 32 – 86 years with mean± SD of 64.87 ± 12.56 years, while that of group B ranged from 34 – 80 years with mean ± SD of 59.47 ± 9.34. group A included 20 (66.6%) males and 10 (33.3%) females. While group B included 19 (63.3%) males and 11 (36.7%) females. Patients of the 2 groups show highly significant difference in SBP, DBP and HR as p value < 0.001. Regarding the laboratory data of the studied patients, there were most patients in group A with leukocytosis (Range 7-60), increased serum creatinine level at admission (up to 14) and serum lactate (47) comparing to those in group B, so there was significant difference between both groups as p value <0.05. Regarding the ECG and radiological investigations of the studied in which there was a significant difference between both groups in ECG and CT chest, as most patients of group A show normal sinus rhythm and normal finding in CT (n=21, 22 respectively) where 18 patients of group B show different abnormalities in their ECG and 19 show pneumonic patches in CT. Regarding the relation between the vital signs and mortality rate, In group A, there were a highly significant effect of SBP, DBP and GCS on mortality rate as P-value was <0.001 and there was non- significant relation between RR, TEMP and survival rate as p value >0.05.In group B, there were a highly significant effect of SBP, DBP, RR, HR and GCS on survival rate as P-value was <0.001 and there was a significant relation between TEMP and it as p value <0.05. According to the sensitivity and specificity of SIRS scores. There was high sensitivity 100% and the specificity was 42.31% for the mortality rate between the studied patients. Regarding the sensitivity and specificity of qSOFA scores. There was high sensitivity 100% and the specificity was 69.32% for the mortality rate between the studied patients.