الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
”Periodontal therapy of intra bony defects represents a major challenge for clinicians. Conventional surgical techniques can not restore the lost tissue architectures and functions. Therefore, some regenerative materials as bone grafts and bone substitutes were developed to achieve this target.
Alloplasts (as bioactive glass) are utilized to overcome the autografts and allograft intrinsic limitations. Thus, the objectives of present study were to evaluate the efficacy of regenerative potentials of bioactive glass bone substitute and to assess clinically and radiographically the platelets rich fibrin (PRF) ability to augment the regenerative ability of bioactive glass bone substitute in stage III grade B periodontitis. : Intra-groups significant improvement in all tested clinical and radiographic parameters (plaque index, gingival index, probing depth index, clinical attachment loss, bone depth and width) were found. However, intergroup comparison showed significant difference only in pocket probing depth were found while non significant difference were found regarding other tested parameters.