الفهرس 
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Abstract
Over 500,000 new instances of hepatocellular carcinoma are detected each year, making it the most common type of primary liver malignancy as well as the second greatest cause of mortality due to cancer.
The vast majority of people who are diagnosed with hepatocellular carcinoma have a history of chronic viral hepatitis that was brought on by either the hepatitis B virus or the hepatitis C virus.
The purpose of this research was to compare the efficacy of Tran’s arterial chemo-embolization as well as radio-frequency ablation in treating hepatocellular carcinoma with and without the use of 3D volumetric imaging.
The results showed that 2D along with Volumetric CT varied significantly in evaluating the therapeutic response of HCC following TACE as well as RF, with only moderate agreement among the two techniques in identifying CR, PR, SD, as well PD. Classifying people as either responders or non-responders using either 2D or Volumetric CT yielded inconsistent results.
This study retrospectively evaluated CT volumetry (comparing both 2D and 3D volumetric CT of the index liver tumor) as a more accurate method for assessing HCC response following trans-arterial chemoembolization & RF-ablation at Minya University Hospital’s radiology department.
The present retrospective cohort research examined 30 Minya University Hospital radiology participants who received interventional therapy for hepatocellular carcinoma with traditional TACE or RF-ablation.
The main results of the study revealed that:
• The mean age was 57 ± 4.7, 70% of cases were male while 30% were female.
• There were 86.7% of our cases had History of HCV, 30% of Cases had Family history of cancer.
• With noted no significance relation between patients’ age and family history with the revealed results regarding response.
• There were 73.3% of our cases had class A while 26.7% had class B Child‐Pugh, 100% of cases had BCLC class B.
• There were 80 % of our cases had Single lesion while 20 % had Multiple, 60% of cases had right lobe affection.
• The mean Pre‐AFP was 405 ± 45 while the post-AFP was 254 ± 31. In Non-Responders, the mean Pre‐AFP was 411 ± 44 while the post-AFP was 378 ± 40. There were high significant difference between Responder and Non-responder as regard laboratory data in our study.
• In 3D volumetric CT, 10% were CR, 50% were PR, 36.7%were SD, 3.3% were PD. 60% were Responders. In 2D CT, 10% were CR, 26.7 %were PR, 60.0% were SD, 3.3% were PD. 36.7% were Responders.
There were significant difference between 3D volumetric CT and 2-D as regard Response data in our study.
• The mean pre treatment tumor index by 2D CT was 5.28 ± 3 while the post treatment was 4.6 ± 2.1. with % (Tc) was 0.31 ± 0.27
• There were high significant difference between Pretreatment and Posttreatment as regard 2D CT data in our study
• The mean pre treatment tumor index by 3D volumetric CT was 74.1± 10.2 while the post- was 32.7 ± 11.2. % (Tc) was 0.67 ± 0.20
• Sensitivity and Specificity of Volumetric 3D was 95% and 92% respectively. Specificity & Sensitivity of CT 2D was 75% also 80% respectively.