الفهرس 
RESPIRATORY ALLERGYOnly 14 pages are availabe for public view
 |  | from | 187 |  |  |
| | | from | 187 | | |
Abstract
Respiratory allergies including asthma, chronic rhinosinusitis and allergic rhinitis, are amongst the most common allergies worldwide and constitute major public health and economic problem for their morbidity and impact on quality of life.
Among the immune allergic diseases of the elderly. The most common disorders were respiratory diseases. chronic respiratory disease is the third most common burden of disease in the elderly aged ≥ 60 years. Although allergic rhinitis (AR) and bronchial asthma (BA) seem to decrease in the elderly, they are often underdiagnosed, undertreated and underestimated in the aspect of the current prevalence rate, although they are common chronic diseases that affect quality of life and further alter mood or cognitive functions.
House dust mites(HDM) are a big source of allergens and can worsen allergies. Most dust mites die in low humidity level (when the humidity falls below 50%) or extreme temperature, but they leave their dead bodies and waste behind to cause allergic reactions
Our study was conducted on 60 patients attending the allergy clinic at Ain Shams University hospitals to evaluate which tool is best in diagnosis of respiratory allergy caused by house dust mites in seniors, skin prick test versus specific IgE.
Our Patients were divided in to two groups seniors (more than 60 years old) and Young (from 15 – 30 years old).
Our study reported the sensitivity of the specific IgE test was 87.9% In the young group, while the skin prick test had a higher sensitivity of 96.7%. Regarding specific IgE test has more specificity by 100% than 50% for the skin prick test. Additionally, in the senior group, both techniques have higher sensitivity, by 96.3% for the specific IgE test and 86.7% for the skin prick test. However, the specificity of both techniques was lower by 50.0%. Both techniques have higher percentages regarding the Positive Predictive Value (PPV). In the young group, the PPV of the specific IgE was 100.0%, while the skin prick test was 96.7%, indicating high confidence in identifications. In contrast, The Negative Predictive (NPV) for the specific IgE test was lower in the young group (20.0%), whereas slightly higher in the skin prick test (48.3%). On the contrary, NPV was higher in the senior group for the specific IgE test (80.0%) versus (50.0%) for the skin prick test. Lastly, the overall accuracy in the young group was 93.1% for the specific IgE test and lowered to 48.3% for the skin prick test. Besides, the overall accuracy in the senior group was 48.1% for the specific IgE test and 42.2% for the skin prick test. Nonetheless, this difference was not statistically significant, P-value> 0.05.