الفهرس 
RADIOLOGICAL ANATOMY OF NORMAL CORONARY ARTERIESOnly 14 pages are availabe for public view
 |  | from | 130 |  |  |
| | | from | 130 | | |
Abstract
• CAD is associated with high mortality around the world. Dyslipidemia, hypertension, diabetes and smoking are common risk factors for CAD.
• CAC and especially progression in CAC is a strong predictor of acute MI and cardiovascular mortality.
• Vitamin K2 supplementation may help inhibit Vascular calcification through anti-inflammatory mechanisms. Vitamin K2 also plays a pivotal role in the activation of extrahepatic γ-carboxyglutamate (Gla) proteins such as MGP, that is commonly considered the strongest inhibitor of vascular calcification.
• Our study was conducted on 30 patients with pre-existing CAD who were randomly assigned in a 1:1 ratio to either oral Vitamin K2 supplementation or no treatment for 6 months. Non contrast cardiac MDCT examination was done at baseline and after 6 months of intervention to detect the change in CAC score.
• We concluded that Vitamin K2 intake can have an important role in decreasing the progression of coronary artery calcification.