الفهرس 
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Abstract
D
ry eye is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film and accompanied by ocular symptoms. Tear film instability and hyperosmolarity, ocular surface inflammation, and neurosensory abnormalities play important role in the etiology of dry eye
The main aim of the study was to compare the corneal epithelial thickness using Anterior segment optical coherence tomography (OCT) in dry eye patients versus healthy individuals.
A prospective case control study was conducted on patients of the outpatient clinic at Ophthalmology department, Faculty of Medicine, Ain-Shams University. The study was conducted on patients in middle age group (from 20 to 50 years old of both sexes). The sample size was 30 dry eyes and 30 normal eyes.
Regarding the demographic characteristics among the studied patients, we found that Age in Dry eyes group ranged from 23 to 47 with mean ± SD = 34.73 ± 8.34 while in Normal eyes group the Age ranged from 25 to 49 with mean ± SD = 35.9 ± 7.01. Regarding the fundus examination among the studied patients, we found that There was a highly significant difference between the two studied groups (p= <.001).
Regarding the AS/OCT-C 5 mm results among the studied patients, we found that Avg. of superior quadrants in Dry eyes group ranged from 47 to 59.6 with mean ± SD = 53.63 ± 3.7 while in Normal eyes group the Avg. of superior quadrants ranged from 49 to 56 with mean ± SD = 52.7 ± 1.93 with no statistically significant difference (p= 0.227) between the two groups. Avg. of inferior quadrants in Dry eyes group ranged from 49 to 65.6 with mean ± SD = 55.62 ± 4.35 while in Normal eyes group the Avg. of inferior quadrants ranged from 49 to 56 with mean ± SD = 52.7 ± 1.93 with statistically significant difference (p= 0.002) between the two groups. Regarding Comparison, there was a highly significant difference between the two studied groups (p= <.001).
Regarding the result (highest thickness) among the studied patients, we found that There was a highly significant difference between the two studied groups (p= <.001).