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Abstract
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females. Inflammatory breast cancer (IBC) is highly metastatic, aggressive and fatal form of breast cancer. Recently, we found that IBC carcinoma tissues contain significantly higher levels of human cytomegalovirus (HCMV) DNA compared to other breast cancer tissues that may regulate cell-signaling pathways. In fact, HCMV pathogenesis and clinical outcome can be statistically associated with multiple HCMV genotypes within IBC. Thus, in the present study, we established the incidence and types of HCMV genotypes present in carcinoma tissues of infected non- IBC versus IBC patients.