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Abstract
Aim: to evaluate the role of novel stocked irrigate that contains acids and antimicrobials as compared with the combined use of acids and antibiotics on contaminated root canals with E. faecalis and their role on eradication of biofilm . Results: group 1 showed the lowest mean count of CFU{u2019}s compared with the other 5 groups. group 2 showed lower mean count of CFU{u2019}s than Groups D1, D2, D1A and D2A but higher than group Q. group 3 and group 4 respectively showed the highest mean count of CFU{u2019}s among other groups. group 5 and group 6 increasing the concentration of doxycycline did not affect significantly the mean bacterial counts while addition of Citric acid 5% to both groups decreased significantly the mean bacterial counts in groups D1A and D2A.