الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 100 |  |  |
| | | from | 100 | | |
Abstract
As much as 25-30% of the world’s population suffers from metabolic associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease. The multi-organ failure of fatty liver disease (MAFLD) has far-reaching effects since it raises the chance of not only liver cirrhosis and failure and hepatocellular carcinoma (HCC), but also of cardiovascular disease, chronic renal disease, type 2 diabetes, osteoporosis, and certain malignancies.
Evidence suggests that there are common genetic risk factors for MAFLD and other metabolic illnesses, indicating that the aetiology of the disease is intricate and includes a dynamic interplay between environmental variables and genetic base. Lean moderate-to-severe obesity-related fatty liver syndrome (MAFLD) is on the rise, despite the disease’s traditional association with obesity. However, there is a lack of characterization of this patient population, which is especially true in the white population.
Diagnosing MAFLD has been made more difficult, therefore recently a global consensus presented additional criteria. In addition to being overweight or obese, having type 2 diabetes mellitus, or showing signs of metabolic dysregulation, hepatic steatosis is a necessary criterion.
Recent research has linked low blood Vitamin D levels to metabolic disorders and nonalcoholic fatty liver disease. Patients with normal liver enzymes are more likely to develop NAFLD if they have hypovitaminosis D. is a cross-sectional research done from June to November of 2022 at Minia University Hospital’s Tropical Department. There were a total of 128 participants who were evaluated using a variety of diagnostic tools (such as x-rays, MRIs, and CT scans) after undergoing a thorough history and physical examination. Fibrosis in the liver was measured using two-dimensional shear wave elastography (2D SWE).
We set out to investigate whether or not Vitamin D levels in the blood were correlated with the presence of metabolic-related fatty liver disease.