الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Increasing life expectancy in the general population and the fact that a disproportional burden of cancer occurs in people aged 65 years and older have generated great interest in delivering better cancer care for older adults. Traditional perioperative risk assessment measures may often overlook subtle geriatric-specific syndromes that translate into increased vulnerabilities for older patients. Comprehensive Geriatric assessment (CGA) has important prognostic value for overall survival (OS), detects unknown geriatric problems in more than 50% of patients with cancer and allows targeted geriatric interventions that can improve quality of life and compliance to therapy. Despite this, a CGA is time consuming, poorly financially rewarded in most health care systems, and not required for every patient. For these reasons, there is increasing interest in the use of geriatric screening tools. These tools are short and easy to administer and can avoid the efforts of doing CGA in fit older patients who do not require extensive CGA.
The aim of this study is to assess the ability of the Geriatric 8 (G8) questionnaire, as a multidomain screening tool which is not routinely used in surgical settings in cancer patients, to predict postoperative outcomes in elderly patients.
We carried out a prospective cohort study on 135 elderly patients above 60 years of age, during the time from February to December 2022, undergoing surgical interventions for malignancies in Ain Shams University Hospitals, Cairo, Egypt. Preoperative assessment was done using the G8 score as well as assessment of comorbidities and functional status. Following their surgeries and during their entire hospital stay, patients were followed and assessed for postoperative complications including mortality, length of hospital stay, return to OR, thromboembolic events, hospital acquired infections and pressure ulcers.
The mean age of our study population was 73 years old. 76.3% were males and 23.7% were females. Upper Git tumors were the most common, followed by colorectal and hepatobiliary. The sensitivity of the G8 score for predicting mortality was found to be 64.9% with 71.4%specificity, 46.2% positive predictive value and 84.3% negative predictive value of mortality, return to OR, hospital acquired infections, length of hospital stay and pressure ulcers, at cutoff score of 7
In a multivariate logistic regression analysis, low G8 and ADL scores were independent risk factors for mortality and return to OR, while low ADLs and IADLs score were independent risk factors for occurrence of hospital acquired infections. However, for the development of pressure ulcers, higher MFI score and lower G8 score were statistically significant independent risk factors.