الفهرس 
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Abstract
Achalasia is a motility disorder characterized by the inability of the lower esophageal sphincter to relax in the setting of absent peristalsis.1 It leads to symptoms of dysphagia, regurgitation of undigested food, chest pain, weight loss, and respiratory symptoms, including nocturnal cough, recurrent aspiration, and pneumonia. Laparoscopic Heller myotomy (LHM) and per-oral endoscopic myotomy (POEM) has been used for the treatment of achalasia.
our meta-analysis provides a better understanding of the comparative efficacy of POEM and HM in patients with achalasia. Although long-term follow-up data in this regard are currently insufficient and considerable heterogeneity was identified in the meta- analysis, the short-term efficacy of POEM was superior to that of HM. The length of myotomy was also greater in POEM than in HM. The operation time and length of hospital stay tended to be shorter in POEM than in HM, however the difference was not big between both. Erosive esophagitis tended to be more common in POEM as fundoplication cannot be done with it.