الفهرس 
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Abstract
COVID-19 is a global pandemic; it caused more than 256 million cases, the increased number of COVID-19 cases and fatalities is a global threat. With early recognition of the cases along with vaccination, the spread of the pandemic can be restrained. Infections often present with non-classical complaints in elderly leading to delayed diagnosis and clinical decision.
COVID-19 infection causes a variety of symptoms that range from asymptomatic or mild cases up to severe cases presented with severe pneumonia with or without multi-organ failure. Studying the different presenting patterns of COVID 19 stratified by age will allow for early identification and hence proper triage of cases.
The CBC is an easily available, inexpensive, and reliable investigation that can help in providing insights into the patients’ COVID-19 status. The combinations of ratio and serial trends of haematology parameters along with clinical assessment can aid in precise decision-making in COVID-19 patient management.
The aim of our study is to evaluate the predictive value of different haematological parameters in determining disease severity and outcomes among elderly patients with COVID 19 admitted at Geriatric isolation hospital, Ain Shams University hospitals during the period from 26/12/2020 to 20/6/2021.
Retrospective evaluation of medical records was used to collect data of 50 patients older than 60 years with proof of SAR-CoV2 by nasopharyngeal swab, Serial complete blood count parameters and other haematological parameters as C-reactive protein (CRP) and ferritin were reported during their admission.
Among those patients, the mean age was 68.5 years, 54% were males. 36% of patients admitted to inpatient ward and 64% admitted in intensive care unit (ICU), The like hood of ICU admission will increased with TLC >10.8 *109/L, Neutrophils >8.81 *109/L, NLR >10.4, CRP >75 mg/L and FERRITIN >603 mcg/L on admission so they can be used as predictors for severity.
The outcome among studied patients was 38% recovered and discharged to home, 36% mortality and 26% referred to other care facility with complications, The likelihood of patients’ mortality will rise with presence high NLR>12.4, CRP>120 mg/L, FERRITIN>493.6 mcg/L and Lymphocytes≤ 0.88 *109/ L on admission so they can be used as predictors for mortality when present on admission.
Through follow up of hematological parameters across length of hospital stay(day 0,7-10 days after admission, at end of hospital stay), there is statistically significant difference in CRP between on admission and at mortality While there is statistically significant difference in Ferritin across the time and between on admission and at mortality, The likelihood of patients’ mortality will rise with increased TLC >10.4 *109/ L, Neutrophils >9.14 *109/ L, NLR >8.1, FERRITIN >510 mcg/L, PLT≤111 *109/ L, Lymphocytes ≤0.82 *109/ L at the end of hospital stay.
But in the studied patients who were transferred to other health facility due to complications showed that, there is statistically significant difference in PLT between on admission and at referral which may support the idea that thrombocytopenia increase risk of complications in patients with COVID 19.