الفهرس 
Title : The effect of vitamin D and swimming exercise on the reproductive system in high fat-fed adult male rats
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Abstract
OBJECTIVES: Study the beneficial effects of vitamin D and exercise against high
fat diet induced insulin resistance and male subfertility in male albino rats.
METHODS: 35 male albino rats treated with high fat diet for 12 successful weeks
and divided into 5 equal groups; each group is 7 rats; (i) normal control rats, (ii) high
fat diet (HFD) group, (iii) received HFD with vitamin D, (iv) received HFD and
swimming exercise, (v) received HFD with vitamin D and swimming exercise.
Blood samples were withdrawn from the experimental animals for analysis of
Glucose, Insulin, Testosterone, FSH, LH, TAG, HDL, LDL, Cholesterol, testis and
prostate were excise to measure antioxidant markers (Glutathione, GPX, Gr, SOD,
MDA and NO).
RESULTS: HFD resulted in insulin resistance characterized by high HOMA IR
values and induced diminished semen quality with alteration in male sex hormones
profile. Treatment with vitamin D and swimming exercise individually showed
marked alleviation of the HFD deleterious effect while combined therapy of both
vitamin D and swimming exercise showed synergistic effects.
CONCLUSION: The use of vitamin D and swimming exercise in the treatment of
insulin resistance and diminished male fertility offered preventive and curative effect
against HFD., especially when combined together.