الفهرس 
Maternal and Fetal PhysiologyOnly 14 pages are availabe for public view
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Abstract
Spinal anaesthesia is the preferred anaesthetic method for elective cs in obstetric anaesthesia practice. Cs normally require an anaesthetic block at T4 level, so hypotension is reported in up to 80% of spinal anaesthesia cases.
Many approaches have been tried to prevent spinal hypotension, e.g., fluid loading, vasopressors, or both. Intravenous fluid protocols have been investigated to prevent spinal hypotension, with unsatisfactory results
Norepinephrine is a weak β-adrenergic and potent α-adrenergic receptor agonist. Therefore, it may be a more suitable option for maintaining maternal blood pressure with less negative effects on heart rate (HR) and cardiac output.
This study aims to compare norepinephrine versus ephedrine in Prevention of hypotension in CS under spinal anaesthesia.
The study was a clinical Prospective, double–blinded and randomized study, the operating theatres of Ain Shams University Hospitals over one year.
We administered the vasopressors by iv infusion when SBP drops 20% below the baseline. We found that no significant difference between both groups regarding fetal Apgar score. We compared two different vasopressors and we chose the regimen of iv infusion.
We found lower numbers of hypotension and hypertension episodes and less frequency of bradycardia and tachycardia in the patients treated with norepinephrine.