الفهرس 
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A- PRF) Versus Platelet Rich Fibrin (PRF) A Randomized Clinical Trial: comparative study
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Abstract
This study was conducted as a randomized controlled clinical trial to evaluate clinically and radiographically the the use of advanced platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction.
sixty patients with at least one non restorable tooth in upper interbicuspid region with systemically healthy conditions, were incorporated into this trial when found eligible. The patients were randomly allocated into three groups (n=20); placing A-PRF after atraumatic extraction of nonrestorable tooth, placing PRF after atraumatic extraction of non-restorable tooth and atraumatic extraction with no additive biomaterial.
Bone caliper was used to clinically measure the change in bone width after 6 months. CBCT was used to measure the change in bone height and bone density at baseline and after 6 months. Soft tissue healing and pain were evaluated using healing index ( Landr et al index ) and visual analog scale respectively.
In our study, no statistically significant difference was found regarding the bone width gain at crest after 6 months between the different groups. group A-PRF group (0.12±0.39 mm), group PRF )0.03±0.26 mm(while normal healing group was)0.05±0.32 mm( with statistical difference in bone width gain at 3 mm from the crest being higher in A-PRF group (0.40±0.48) other than two groups. No statistically significant difference between the test and the control groups regarding bone height, density, soft tissue healing and pain was found.
Alveolar ridge preservation using advanced Platelet rich fibrin (A-PRF) and platelet rich fibrin (PRF) showed noticeably superior results when it comes to soft tissues healing and postoperative pain. On the other hand, there was no clinically tangible difference with regards to hard tissue changes with a limited effect of A-PRF on hard tissue healing.