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العنوان
Rapid detection of carbapenemase producing enterobacteriaceae using chromID® CARBA agar /
الناشر
Emad Sayed Ewis ,
المؤلف
Emad Sayed Ewis
هيئة الاعداد
باحث / Emad Sayed Ewis
مشرف / Mona Abdelaziz Wassef
مشرف / Walaa Aboulkasem Ismail Shahin
مشرف / Doaa Mohammad Abdelatty Ghaith
تاريخ النشر
2016
عدد الصفحات
167 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء الحيوية (الطبية)
تاريخ الإجازة
11/5/2016
مكان الإجازة
جامعة القاهرة - كلية الطب - Clinical and Chemical Pathology
الفهرس
Only 14 pages are availabe for public view

from 180

from 180

Abstract

With the increase in the use of carbapenems, the number of resistant bacteria with different resistance mechanisms is rising. Some resistance mechanisms include deactivating antibiotics, altering or producing excessive amount of drug target receptors by protein gene mutation, acquiring a new gene that produces insusceptible target, reducing the permeability of cell membrane to antibiotics and also removing active drug from periplasm or from inside of cell. Among the most important resistance mechanisms against carbapenem is producing carbapenemase The increased worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) emphasizes the need for a sensitive screening procedure to identify these microorganisms.Gastrointestinal carriers may serve as the reservoir for cross-transmission in the health care setting, and thus active surveillance is a key part in preventing the spread of such strains.Method: in our study a new chrom ID CARBA AGAR (Biomerieux) was used for rapid detection of CRE cases in different departments of Abo elreish hospital. Results and conclusion: It was found that the prevalence of CRE carriers is 70 % in different departments. The sensitivity of chrom ID CARBA AGAR was 100 % and the Specificity was 80 %