الفهرس 
Anatomy of Taste and Paranasal SinusesOnly 14 pages are availabe for public view
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Abstract
Background: chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the mucosa of the nasal cavity and nasal sinuses. Many patients with chronic rhinosinusitis complain of gustatory dysfunction which affects their quality of life.
Objective: The aim of this work is to assess the gustatory function and acuity in patients with chronic rhinosinusitis using taste strips.
Subjects and Methods: This is a case control study carried out at Department of Otorhinolaryngology at Ain Shams University Hospitals from May 2021 to June 2022 on 63 Patients with chronic rhinosinusitis with nasal polyposis and 63 normal controls. All patients of the study and control group will be subjected to full medical history taking including SNOT-22-Questionnaire, endoscopic nasal examination, computed tomography scan nose and paranasal sinuses using Lund-Mackay score. Taste strips representing five tastes (sweet, sour, salty, bitter and umami) were used to assess gustatory function in CRS patients and controls.
Results: Sixty-three patients with CRS and sixty-three healthy controls were involved in our study. Their age were 42.05± 14 years old for cases and 40.9± 13.6 years old for controls. There was a highly significant difference between cases and controls as regard SNOT-22-Questionnaire score, Meltzer-score and Lund-Mackay score with higher mean scores among cases. There was a highly significant difference between cases and controls as regard Sweet, Salt Sour, Bitter, Umami and Total Taste score, with lower mean scores among cases. This is most evident in bitter taste. There was a significant negative Correlation between each of SNOT-22-Questionnaire score, Meltzer-score and Lund-Mackay score and Total Taste Score.
Conclusion: Patients with CRS exhibited decreased gustatory function compared to healthy controls. The effect was most pronounced for bitter taste.