الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Diabetes mellitus (DM) is a metabolic disorder characterised by chronic hyperglycemia caused by insulin resistance (IR) or impaired insulin production. Objective: To evaluate relation between serum zinc level and diabetic retinopathy in patients with type 2 diabetes mellitus. Subjects and Methods: We collect 60 subjects with their ages ranging from 18-60, selected from diabetes and opthalmology outpatient clinics of Ain Shams University Hospitals for 7 months in a period from June 2022 to July 2023. The current study included 60 subjects with their ages ranging from 18-60, selected from diabetes and opthalmology outpatient clinics of Ain Shams University Hospitals for 7 months in a period from July 2022 to January 2023. Results: There is statistically significant difference between DM type II subgroups g regarding duration of disease (yrs) being higher in DM II with retinopathy 12.5 (10.5 – 16.5) than DM II without retinopathy 9 (6 – 12) with p <0.001. There is no statistically significant difference found between control group and DM type II group regarding weight, height and BMI of the studied patients with p-value = 0.108, 0.198 and 0.343; respectively. There is no statistically significant difference found between control group and DM type II group regarding systolic and diastolic blood pressure of the studied patients with p-value = 0.554 and 0.405; respectively. There is no statistically significant difference found between control group and DM type II subgroups regarding gender and age of the studied patients with p-value = 0.059 and 0.108; respectively. Conclusion: Our study suggested that lower serum zinc level in T2D patients was related to higher prevalence of diabetic microvascular complications. Patients with lower serum zinc level were more likely to have a longer duration of diabetes, poorer glucose control, and worse β-cell function. Older age, higher HbA1c level, and the prevalence of DN were risk factors related to the lower serum zinc level. |