الفهرس 
Review of LiteratureOnly 14 pages are availabe for public view
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Abstract
P
ost operative sore throat (POST) is a common complication following general anesthesia requiring endotracheal intubation with incidence ranges from 21% to 65%, also it may consider a minor complication, but if left unresolved, it produces significant agony and annoyance to the patients, if it was severe, it may be associated with hoarseness of voice or change of voice.
Multiple pharmacological and non-pharmacological methods have been used to decrease incidence and severity of POST. The pharmacological methods include use of beclomethasone gel, lidocaine spray, ketamine gargle, magnesium gargle, ketamine nebulization and magnesium nebulization. While nonpharmacological methods include smaller sizes of tracheal tube, careful airway manipulation, intubation after complete muscle relaxation, minimizing the number of laryngoscopy trials for intubation, fixation of endo tracheal tube intra cuff pressure at or below 20 cm H2O, gentle pharyngeal suctioning under vision and extubation when the tracheal tube cuff is fully deflated. All these methods have been reported to decrease the incidence and severity of POST.
In our study we compare ketamine nebulization and magnesium sulphate nebulization to evaluate their efficacy in decreasing incidence and severity of POST and concluding which drug is better.
The result of the study showed that preoperative nebulization with ketamine 50mg is more effective than preoperative nebulization with magnesium sulfate 250mg in reducing incidence and severity of post operative sore throat especially early after operation.