Search In this Thesis
   Search In this Thesis  
العنوان
Association between serum iron and the severity of coronary artery disease /
المؤلف
Ahmed, Mohamed Nagy Osman.
هيئة الاعداد
باحث / محمد ناجي عثمان أحمد
مشرف / محمود محمد عبده يوسف
مشرف / أحمد ابراهيم بدير عبدالنبي
مناقش / وائل محمد راغب رفاعى
مناقش / سامح اميل صادق ذكى
الموضوع
Coronary artery bypass. Coronary Artery Disease. Heart failure.
تاريخ النشر
2023.
عدد الصفحات
online resource (98 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم أمراض القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

from 114

from 114

Abstract

Coronary artery disease is most commonly due to obstruction of the coronary arteries by an atheromatous plaque. The risk factors for atherothrombotic CAD are smoking, hypertension, Diabetes mellitus, dyslipidemia and obesity. The diagnostic investigation for obstructing coronary lesions is the coronary angiogram. Via iron-dependent enzymatic processes, iron has a pivotal role in maintaining the cellular function and integrity and mediates a variety of metabolic processes. However, careful homeostasis is also critical as both iron-deficient (e.g. skeletal muscle dysfunction) and overload (e.g.hemochromatosis) states can be deleterious to the human body. For the first time, (Sullivan., 1981) suggested time that iron stores in human body may be positively correlated with the risk of coronary heart disease. According to his hypothesis, production of free radicals that are subsequently modified to low density lipoprotein cholesterol (LDL) is important in the development of atherosclerosis and iron may stimulate the catalyzing of oxidation reactions that produce free radicals.