الفهرس 
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Abstract
Sepsis-associated acute kidney injury (S-AKI) is a common complication in hospitalized and critically ill patients, which increases the risk of developing chronic comorbidities and is associated with extremely high mortality.
AKI in trauma patients is multifaceted and its etiology is diverse, renal ischemia being the most common cause.
The aim of this study is to evaluate the incidence and outcome of AKI in intra-abdominal sepsis, regarding to the admission way, length of hospital stay, mortality or survival within one week.
This study included 200 patients who presented to the Emergency Department, Menoufia University Hospitals and Al-kasr Alainy in a trauma event.
The studied patients were divided into 2 Groups:
group A: Traumatic patient controlling group with AKI included 100 patients.
group B: Intra-abdominal sepsis patient with AKI included 100 patients.
All patients were subjected to full history taking, assessed and managed through (ATLS) protocol including:
1. Primary survey.
2. Secondary survey.
3. Investigations.
4. Outcome: in the form of (admission to ICU or word, Length of hospital stay, Mortality or survival within one week).
Management of AKI: (Dialysis or Conservative).
The results of this study within the limitations of this study shown that:
- The mean ± SD of the studied patients, was 46.02±17.14 in group 1 and 36.12±24.15 in group II and the majority of them were males (59% &63% of group I and II respectively)
- The predominant primary diagnosis of the patients responsible for hospitalization in which most patients were diagnosed as perforated appendix, abdominal collection, secondary intra-abdominal sepsis, secondary peritonitis, ascending collangitis, perforated viscus, mesenteric vascular ischemia and complicated acute appendicitis (18, 12,15,7, 8, 8, 3 and 6 respectively).
- It was found that, most of the patients in group I did not develop AKI (87%), 13% developed AKI.
- There were a highly significant relation between development of AKI and ICU admission with increasing mortality rate as P-value <0.001in group I.
- In our study, the hospitalization and treatment periods (Length of stay) for AKI patients in critical condition were longer in group I than group II, and there was non-significant relation between hospital stay and AKI development or patients outcomes.
- Also there were a highly significant relation in group II between development of AKI on word or ICU admission and mortality rate as P-value <0.001
- In the present study, the overall mortality rate was 22%, which was significantly higher for AKI group, AKI is associated with a significant risk of morbidity and mortality.