الفهرس 
Thoracoscopic talc insufflation versus doxycycline pleurodesis for the management of malignant pleural effusion
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Abstract
Malignant pleural effusions (MPEs) can be a complication of virtually any malignancy. Quality of life with MPE is often compromised due to debilitating symptoms like dyspnea, cough, orthopnea,chest pain or pressure. There are several approaches to MPE management, with the objective of each procedure to drain the pleural space and to relieve respiratory symptoms. If the MPE recurs after intial thoracentesis, several approaches can be taken for further control: repeat thoracentesis, placement of tunneled pleural catheter (TPC), tube thoracostomy with pleurodesis, or medical pleuroscopy with pleurodesis. Wide spread practice variation in performing pleurodesis would underscore the importance of appropriate clinical trials to determine the best clinical practices in performing pleurodesis. This study was performed to compare 2 widely used pleurodesis techniques, tube thoracostomy doxycycline pleurodesis and thoracoscopic talc insufflation, aiming to explore the effectiveness and safety of both procedures. Thirty patients with documented MPE were selected and divided into 2 groups, subjects of group1 (20 patients) were managed by thoracoscopic talc insufflation and subjects of group 2 (10 patients) were managed by tube thoracostomy doxycycline pleurodesis