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العنوان
Biochemical studies on the different effects of some Eggplant extracts /
الناشر
Rehab Salah Sayed Mahmoud ,
المؤلف
Rehab Salah Sayed Mahmoud
هيئة الاعداد
باحث / Rehab Salah Sayed Mahmoud
مشرف / Ebtsam Abdelmoniem Mahmoud
مشرف / Sayed Abdelkader Fayed
مشرف / Khaled Abdelrahim Elsawy
تاريخ النشر
2018
عدد الصفحات
124 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الزراعية والعلوم البيولوجية (المتنوعة)
تاريخ الإجازة
10/9/2018
مكان الإجازة
جامعة القاهرة - كلية الزراعة - Agriculture Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 170

from 170

Abstract

The effect of solvent polarity on the total phenols extracted from eggplant peel varieties as well as its antioxidant, antimicrobial and anticancer avtivity were studied.As the solvent polarity increases, the total of yield extract, total phenolic (TP) and total flavonoid (TF) increased. Phen-1,3-diol,4,5,6-trimethoxy-2-propionyl (1.43-15.16%) and 1-Naphthalenol (1.58-14.73%) were the major compounds identified by GC/MS/MS in propan-2-ol and methanol extracts, respectively. Both methanol and propan-2-ol extracts exhibited higher antioxidant activities, DPPH radical scavenging activity and ferric reducing power (FRP), than n-hexan extract. Among eggplant varieties, TP and TF compounds obtained from peel of round black were higher than these obtained from long black and long purple varieties in all three solvents. All EPP successive extracts showed anticancer effects against both breast (MCF-7) and liver (HepG2) cancer cells, and it’s had the strongest inhibition against HepG2 cells, while had moderate inhibition against MCF-7 cells. The methanol and propanol extracts showed high antibacterial activity, especially gram positive bacteria, while the hexane extract showed very low anti-bacterial activity, while all extracts showed an activity against fungus. Round black eggplant peel extract was the most active against of both breast and liver cancer compared to other species. Methanol direct MD extract, which had lowest TP and TF content compared with methanol successive (MS0 extract, exhibited the highest DPPH radical scavenging activity and the highest FRP in all three EPP varieties. MD extracts had the strongest inhibition against breast cancer cell line (MCF-7 cells) with IC50 values ranged from 17.0-21.6 og/ml, whereas MS extracts had the strongest inhibition against liver cancer cell line (HepG2 cells) with IC50 values ranged from 19.7{u2013}25.2 og/ml. MD extract had higher antibacterial activity than MS extract against most Gram negative bacteria