الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Asthma is a chronic inflammatory disease of airways. chronic bronchial asthma may cause pulmonary arterial hypertension, which causes RV hypertrophy and dilatation, RV Systolic and diastolic dysfunction. The level of right ventricular dysfunction depends on the degree of right ventricular hypertrophy and total pulmonary resistance.
Aim of the study: The aim of this study was to evaluate atrial electromechanical delay (AED) and P wave dispersion in bronchial asthma.
Patients and methods: This study included thirty-eight patients with bronchial asthma and 38 control subjects. All patents were subjected full history taking, clinical examination and they underwent 12 lead ECG and Echocardiography including tissue Doppler examination. Cases with bronchial asthma were divided into two groups based on medication used for disease control
group 1 patients were maintained on Inhaled corticosteroid fluticasone, Inhaled short acting beta2 agonist PRN and anti-histamine medication. group 2 patients were kept on Inhaled corticosteroid fluticasone long acting β2 agonist, montelukast and Inhaled short acting β2 agonist PRN
Results: Tricuspid Annular É, Á and S waves Velocities were significantly lower in cases. AED was significantly higher in cases. No significant correlation was found between P wave dispersion and AED. Significant area under ROC curve was found with AED cutoff >33 ms. Sensitivity of AED for detection of RV dysfunction was 65.8%, specificity was 68.4% and accuracy was 67.1%. PWD was significantly higher in group 2 compared to group 1.
Conclusion: Early and late subclinical biventricular diastolic dysfunction and right ventricular systolic dysfunction were detectable in children with bronchial asthma using tissue Doppler echocardiography. P wave dispersion was higher in patients with bronchial asthma denoting variable duration of atrial depolarization among these patients.
Atrial electromechanical delay was higher in children with bronchial asthma denoting impairment of atrial conduction. Atrial electromechanical delay was almost 66% and 68% sensitive and specific for predication of RV diastolic dysfunction in children with bronchial asthma.