الفهرس | Only 14 pages are availabe for public view |
Abstract Probiotics have been widely explored in food processing, production, research and disease prevention, therefore, the present study was conducted to evaluate the effect of two regimen diet including high fat diet and basal diet supplemented with Rayeb, vitamin D and their mixture on obese rats for 8 weeks. The rats (n=63) were classified into 9 groups, as follows: group (1): fed on basal diet and kept as negative control group. While the remainder rats (n= 56) were fed on high fat diet for four weeks to induce obesity then were divided into eight groups, group (2) was fed only on high fat diet and served as control positive group. Groups (3, 4, 5): obese rats were fed on high fat diet and were given orally 1 ml of fermented milk “Rayeb”, Vitamin D (600 IU/Kg BW), and their mixture respectively. The other obese groups were continued the experiment on basal diet, as group (6) was fed only on basal diet and served as control positive group. Groups (7,8, 9): obese rats were fed on basal diet and were given orally 1 ml of fermented milk “Rayeb”, Vitamin D at 600 IU/Kg BW, and their mixture, respectively. The results indicated that, the supplementation with Rayeb, vitamin D and their mixture significantly (P<0.05) decreased the final body weight and VI BWG% as compared to the positive control group due to lowering the feed intake and the feed efficiency ratio of the obese rats as well as improving the liver and kidney functions and lipid profile of the obese rats. Moreover, the concentration of leptin hormone and the percent of peritoneal fat bad were significantly (P<0.05) lowered for all treated groups. On the other hand, the basal diet supplemented with Vit D and Rayeb significantly (P<0.05) decreased the body weight more than the high fat diet that supplemented with the same tested materials. The highest weight reduction was observed at the group fed on basal diet and supplemented with a mixture of the tested materials. It could be concluded that, consumption of fermented milk (Rayeb), vitamin D and/or their mixture might be useful in weight reduction. Key words:fermented milk (Rayeb), vitamin D, obesity, weight, liver and kidney functions. |