الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 249 |  |  |
| | | from | 249 | | |
Abstract
Multiple studies report on the use of DWI and DTI for differentiating high-grade glioma from solitary brain metastasis based on the measurements of FA and ADC in the intra-tumoral enhancing components and peri-tumoral edema.
Most brain tumors are surrounded by a high T2 -signal abnormality that has been described as “peri-tumoral edema.” (Oh et al., 2005). In metastatic brain tumors peritumoral edema is referred as vasogenic edema with no tumor cells are present (Lee et al., 2011). In glioma, however, peritumoral edema is better referred to as “infiltrative edema” because it represents vasogenic edema and infiltrating tumor cells (Lee et al., 2011). Differentiation of vasogenic edema from infiltrative edema has been attempted using DWI on the basis of the premise that water diffusivity is facilitated to a greater degree in vasogenic edema than in infiltrative edema because of a lack of intervening tumor cells in the former (Cha et al., 2006).
Our study showed that DTI is valuable tool in differentiation between brain metastasis and high-grade gliomas using FA and ADC maps measured in the peri-tumoral edema with elevated values of FA and ADC in metastases than HGG.