Search In this Thesis
   Search In this Thesis  
العنوان
Evaluation of PD-L1 Immunohistochemical Expression And Tumour Infiltrating Lymphocytes In Different Types Of Endometrial Carcinoma \
المؤلف
El-Rashedy, Mariam Mahmoud Seleem.
هيئة الاعداد
باحث / مريم محمود سليم الرشيدى
مشرف / رجاء أحمد سالم
مشرف / ليلي نابغ محمد نجيب
مشرف / ريهام محمد أبوزيد
تاريخ النشر
2022.
عدد الصفحات
255 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض الدم
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - الباثولوجيا
الفهرس
Only 14 pages are availabe for public view

from 255

from 255

Abstract

Endometrial cancer (EC) identified at an early stage is successfully treated in a majority of patients with surgery with or without radiotherapy or chemotherapy. For patients with advanced disease, however, the prognosis is poor; 5-year survival rates are less than 50% in patients with lymph node metastases and less than 20% in those with peritoneal or distant metastases (Herzog,2015). Previous studies proved that PD1-/PD-L1 blockers are currently effectively used as immunotherapies in a number of tumors such as melanoma and non-small cell lung cancer. This study is conducted to determine the expression of PD-L1 in endometrial carcinoma and to assess its potential role as a biomarker for different types that can be used to screen candidates fit for immunotherapy. (Gasparri,et al.,2017)