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العنوان
Assessment of metabolic disturbances and their effects on epilepsy outcome in patients with juvenile myoclonic epilepsy /
المؤلف
Shehab El-Din, Noha Mohamed Saad.
هيئة الاعداد
باحث / نهى محمد سعد شهاب الدين
مشرف / إبراهيم السيد حسن المنشاوي
مشرف / أحمد عبدالخالق عبدالرازق
مشرف / شيرين صلاح متولي
مشرف / محمد سعيد جمعه
مناقش / أشرف عبدالمنعم أحمد المتولي
مناقش / محمود حميده محمود الرقاوي
الموضوع
Epilepsy - Etiology. Epilepsy - Treatment. Brain - Models.
تاريخ النشر
2022.
عدد الصفحات
online resource (164 pages) :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأعصاب السريري
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب المخ والاعصاب
الفهرس
Only 14 pages are availabe for public view

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from 164

Abstract

Epilepsy is one of the most common neurologic problems worldwide. According to research, 3 per cent of persons in the general population will have epilepsy at some point in their lives. Approximately, 724,500 people with epilepsy live in the Arab world. Juvenile myoclonic epilepsy (JME) is a common epilepsy syndrome that is classified as one of the idiopathic generalized epilepsies (IGEs). It includes a group of seizure patterns that are clinically distinct from those in other forms of IGE, with the major characteristic being adolescence-onset myoclonic seizures. Although the pathogenesis is not clearly understood, several possible mechanisms are suggested. The relationship between obesity and epilepsy is a rich and interesting area for research. There are potential reasons to consider that patients with epilepsy have a higher risk of developing obesity than the general population. First, epilepsy itself may cause progressive weight gain through central nervous system (CNS) pathways. Second, bodyweight gain is a known common and frequent undesirable effect associated with the use of antiepileptic drugs. This has been observed for many years with valproic acid (sodium valproate) and carbamazepine, and also, more recently, with some of the newer antiepileptics such as vigabatrin and gabapentin. Finally, some studies have found that patients with epilepsy participate less frequently in physical activities than the general population. This restriction has been explained, partly due to fears of either injury during seizures or the possibility of exercise-induced seizures.