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During the two consecutive winter seasons of 2015 and 2016 at Faculty of Agric.; Damietta university, New Damietta City, Damietta Governorate, Egypt, pot experiment was conducted to examine the effect of phosphorus fertilization, organic fertilization and inoculation with Azotobacter as well as their interactions on growth, chemical constituents and yield of soybean plants (Glycine max L.). from the above study it can be concluded that integration of inorganic fertilizers with biological and organic manure enhanced the yield attributes such as Pod length, pod weight, Weight of 100 seeds (seed index) and Seed yield. The highest seed yield were recorded in the treatment 55 kg.fed-1 P2O5 through phosphorus fertilizers coupled with chicken manure at the rate of 12 ton.fed-1 and Azotobacter. Similarly, the highest chemical content was also obtained from the integration of 55 kg.fed-1 P2O5 through phosphorus fertilizers coupled with chicken manure at the rate of 12 ton.fed-1 and Azotobacter. Thus the objective of maximizing yields as well as maintaining soil health and productivity can be furnished by a balanced use of inorganic fertilizers conjunctively with biological and organic.