الفهرس 
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Abstract
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide prevalence of 25%. Considering the continuing obesity epidemic, the rise in diabetes, and other factors, the prevalence of NAFLD along with the proportion of those with advanced liver disease is projected to continue to increase.
Liver biopsy is the test for diagnosis and staging of NAFLD, but nowadays several non-invasive biochemical markers, scoring systems, and imaging studies are available to diagnose and stage NAFLD.
Non-invasive imaging methods are rapidly evolving and may replace biopsy in some circumstances. These methods include well-established techniques, such as conventional ultrasonography, computed tomography, and magnetic resonance imaging and newer imaging technologies, such as ultrasound elastography, quantitative ultrasound techniques, magnetic resonance elastography, and magnetic resonance-based fat quantitation techniques.
Various studies done to assess the vascular dynamics of liver in patients with fatty liver disease have shown that with increasing severity of NAFLD there are significant changes in the hemodynamics of the hepatic circulation which can determine the prognosis of the condition.
Summary
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In our study 80 individuals were recruited from Internal Medicine and Hepatology outpatient clinics at Ain Shams University Hospitals from December 2018 till June 2020. 60 of them are diagnosed as fatty liver and classified into 3 grades of NAFLD by ultrasound and transient elastography and 20 are taken as healthy control.
Doppler ultrasound was done to all patients and control groups for assessment of portal vein and hepatic artery hemodynamics.
Results show that there are significant hemodynamics changes seen in the portal vein and the hepatic artery in patients with fatty liver and these changes correlated with the grading of the severity of the fatty liver.
The Vmax, MFV, VPI and Vmin of the portal vein was decreased significantly in subjects with fatty liver suggesting a reduced portal flow while the HARI was found to be significantly lesser in fatty liver suggesting an increased hepatic artery blood flow