الفهرس 
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Abstract
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UMMARY
ypocalcemia is the most frequent complication after thyroid surgery.
When hypocalcemia is predicted, treatment with prophylactic calcium and vitamin D supplements can prevent the development of hypocalcemia symptoms and premature discharge of patients.
This study aims to clarify factors related to the patient as well as surgical methods to find significant correlations between them and early hypocalcemia development.
11 articles were included. This review has demonstrated that perioperative PTH concentration, preoperative vitamin D level, and early postoperative changes in calcium levels are useful biochemical predictors of post-thyroidectomy hypocalcaemia.
Clinical predictors that had a higher significant association with post thyroidectomy hypocalcemia included female patients than male [OR = 0.625, 95% CI (0.420–0.932), p-value=0.021], patients who underwent autotransplantation than those with no autotransplantation group [OR = 2.020, 95% CI (0.968–4.215), p-value=0.061] and those with cervical LN dissection than those who didn‟t have cervical LN dissection [OR = 1.680, 95% CI (1.054–2.679), p-value=0.029].
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Summary
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Clinical predictors that had higher but insignificant association with post thyroidectomy hypocalcemia included patients with Graves’ disease than non- Graves’ patients [Odds ratio (OR) = 1.054, 95% CI (0.623–1.784), p-value=0.844], patients with more than two parathyroid glands preserved than with those had less than or equal two parathyroid glands preserved [OR = 1.131, 95% CI (0.259–4.939), p-value=0.870] and those for whom reoperation wasn‟t done than those for whom reoperation was done [OR = 0.963, 95% CI (0.594–1.563), p-value=0.879].
The following factors were not associated with post-thyroidectomy hypocalcaemia in our meta-analysis: menopausal status, ethnicity, concomitant thyroiditis, use of antithyroid drugs, period of administration of antithyroid drugs, use of cortisone, body mass index and postoperative cord palsy