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العنوان
Risk Factors and Predictors of Occlusion of Stent of Trans Jugular Intrahepatic Porto-systemic Shunt (TIPSS) in Egyptian Patients with Primary Budd Chiari Syndrome /
المؤلف
Dawoud, Ibrahim Abd El-Hakim Ibrahim Hindy.
هيئة الاعداد
باحث / ابراهيم عبد الحكيم ابراهيم هندى داود
مشرف / فاطمة أحمد على الدين
مشرف / محمد الغريب أبو المعاطي
مشرف / هبة رشاد عطية
تاريخ النشر
2021.
عدد الصفحات
136 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - طب المناطق الحارة
الفهرس
Only 14 pages are availabe for public view

from 136

from 136

Abstract

Budd Chiari syndrome is a rare disorder which is characterized by hepatic venous outflow tract obstruction. The classical triad of presentation are ascites, hepatomegaly and abdominal pain.
Early diagnosis and proper treatment improve the overall survival and decreases morbidity and mortality, anticoagulation is main line of treatment, angioplasty, stenting and TIPSS provides way of decompression of the congested liver.
TIPSS is used as the most common line of treatment in treating BCS patients with good outcome in case of good patient selection.
Despite the long-time of experience through this technique, there are predictable complications during and following the maneuver ranging from stent occlusion, sepsis and bleeding up to death.
TIPSS occlusion remains a major problem after intervention which require regular follow up and shunt revision for proper identification and restoring patency.
This retrospective study aims to identify possible risk factors for TIPSS occlusion.
Patients presented to BCS outpatient clinic, Tropical medicine department, Ain Shams University Hospitals were enrolled in the study from 2005 to 2020.
The included patients were adult primary BCS patients who underwent TIPSS and receiving appropriate medical treatment and good management of their etiology. The included patients were divided in 2 groups according to stent patency and compared regarding their data
History, clinical examination, pre and post TIPSS laboratory data, Duplex ultrasound testing the stent patency was done after intervention at day 1, day 7, 3 months, 6 months.
76 BCS patients were included. The mean age of the patients was (29.29 ± 7.92) with female predominance, Females were 61.8% in the studied population. the main presentations were ascites (88.2%), abdominal pain (89.5%) and hepatomegaly (75.0%)
The prevalent thrombophilia etiology in the studied group was FVLM (69.7%) then MTHFRD (67.1%).
The overall rate of stent occlusion in 6 months among the patients was 50 % with highest rate of occlusion at 7 days post TIPSS and 3 months.
After analyzing the results, we found that there is no significant relation between age, sex and TIPSS stent occlusion. Different etiologies of BCS may be a risk factor for stent occlusion. Patients with AT III deficiency and PRV carried a higher rate of occlusion. Also cirrhotic and coarse liver by ultrasound may predict stent occlusion.