الفهرس 
Malignant Pleural Effusion
MEDICAL THORACOSCOPYOnly 14 pages are availabe for public view
 |  | from | 168 |  |  |
| | | from | 168 | | |
Abstract
Malignant pleural effusion is one of the most harmful hazards of cancer as most patients become disturbed mainly from dyspnea that can interfere with life quality. Actually, the goal of pleurodesis in these patients is to prevent reaccumulation of pleural fluid which forces the patients to frequent thoracentesis. The aim of this study was to compare the efficacy and safety of silver nitrate versus doxycycline in thoracoscopic pleurodesis as a management tool in recurrent malignant pleural effusions. This study was executed in the chest department of Tanta University Hospital on 40 patients had recurrent malignant pleural effusion. These patients were randomly assigned in to two groups; group I: included 20 patients afforded thoracoscopic pleurodesis through 50 ml 0.5% silver nitrate, and group II: included 20 patients afforded thoracoscopic pleurodesis through 1 g doxycycline dissolved in 50 ml normal saline. Patients included in this study showed large amount of pleural effusion associated with symptomatic dyspnea and lasted for more than 3 weeks. They also had cytologically or biopsy confirmed malignant pleural effusion, and had radiological evidence of lung expansion after drainage of pleural effusion.
Patients who had cardiovascular instability, fever, infection, coagulation defects, trapped lung, endobronchial obstruction, pulmonary fibrosis, hypersensitivity to silver nitrate or doxycycline, less than one month life expectancy, air leak and history of previous pleurodesis were excluded from this study.