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العنوان
Management of Vestibular Schwannoma \
المؤلف
Ali, Hisham Tawfick.
هيئة الاعداد
باحث / هشام توفيق علي فهمي
مشرف / حسين السيد محمد محرم
مشرف / أحمد السيد عبدالبر
مشرف / صلاح مصطفي حماده
تاريخ النشر
2021.
عدد الصفحات
177 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأعصاب السريري
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - جراحة المخ و الاعصاب
الفهرس
Only 14 pages are availabe for public view

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Abstract

Background: Vestibular schwannoma (VS) is considered histologically a benign tumor and is currently preferred over the older term (Acoustic neuroma) as it usually arises from the inferior division of the vestibular nerve and not the acoustic nerve in the cerebellopontine angle. VS were one of the most common intra cranial tumors, comprising 8-10% of tumors in most series. Annual incidence is probably about 1.5 cases per 100,000 population, over the past couple decades this estimate has increased and the typical size at the initial diagnosis has decreased as a result of the advances in the MRI scans & CT scan qualities, (VS) is found to be occurring among middle age groups with no gender prevalence in the fourth or fifth decade.
Aim of the Work: To evaluate the VS management especially partial resection of large VS followed by gamma knife.
Patients and Methods: This study is a retrospective prospective study. This study was carried out at Al-Demerdash University hospital, the authority of specialized institutes and teaching hospitals and international medical Centre (Gamma knife department). Time of the study: from March 2019 till March 2021.
Results: In this study we found that according to the demographic, characteristics & personal history of the study group, it is noted that vestibular shwannoma is common among middle aged group (mean =41 years), with no substantial difference between genders (53% F & 47% M), we found that as regard the clinical picture, most of patients suffered from hearing loss as a complaint (88%) of about 3.5 months duration (median IQR) while all the patients (100%) had a sensory neural sensory loss and verified by PTA, SDT & word discrimination, tinnitus & unsteadiness were found in 70% & 50% respectively. This study has some limitations which are small populations of patients with vestibular schwannoma who generally have short follow-up. We include patients with heterogeneous tumors in regard to size and hearing status. Further studies needed with large populations to establish our results.
Conclusion: We concluded that considering the good tumor growth control and facial nerve function preservation as well as the possibility of preserving serviceable hearing and the low number of complications, subtotal resection followed by Gamma knife can be the treatment option of choice for large Vestibular schwannoma.