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العنوان
Prediction of Preterm Labour by Ultrasonic Markers in Women at High Risk /
المؤلف
Abutekia, Eman Mohamed Abdulmonem .
هيئة الاعداد
باحث / إيمان محمد عبدالمنعم أبوتكية
مشرف / أيمن عبد القادر شبانه
مناقش / محمد عبدالله رزق
مناقش / عادل الشحات السيد الجرجاوى
الموضوع
Premature labor. Premature Birth diagnosis. Labor (Obstetrics) Complications. Preeclampsia.
تاريخ النشر
2021.
عدد الصفحات
70 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
16/6/2021
مكان الإجازة
جامعة المنوفية - كلية الطب - قسم أمراض النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

race, and low maternal body-mass index and short cervical length. The rate of preterm birth has increased in many locations, predominantly because of increasing indicated preterm births and preterm delivery of artificially conceived multiple pregnancies.
Common reasons for indicated preterm births include pre-eclampsia or eclampsia, and intrauterine growth restriction. Births that follow spontaneous preterm labour and preterm premature rupture of membrane together called spontaneous preterm births are regarded as a syndrome resulting from multiple causes, including infection or inflammation, vascular disease, and uterine overdistension. Risk factors for spontaneous preterm births include a previous preterm birth, black race and low maternal body-mass index and short cervical length. The rate of preterm birth has increased in many locations, predominantly because of increasing indicated preterm births and preterm delivery of artificially conceived multiple pregnancies.
Uterocervical angle (UCA) represents a novel ultrasonographic marker that is defined as the triangular segment measured between the lower uterine segment and the cervical canal. The current study aimed to study the role of measuring of length of cervical canal and uterocervical angle (UCA) as ultrasonic predictive markers for woman at high risk of preterm labor. The is a prospective cohort study conducted at Obstetrics and Gynecology department at Menoufia University Hospital and Ashmon one day surgeries Hospital during the study period from July 2019 till December 2021.
Pregnant women included in this study were divided in to two groups as follow:
• Study group: included 50 pregnant women at 24-34 weeks at high risk of preterm labor in whom cervical length and uterocervical angle was measured.
• Control group: included 50 healthy pregnant women at 24-34 weeks during routine antenatal care and in whom cervical length and uterocervical angle was measured.
Inclusion criteria: Pregnant women age ranged between 18-35 years, at high risk of preterm labor as, history of previous preterm labor, history of having low birth weight baby, history of bleeding during first or second trimester, multiple pregnancy, had in vitro fertilization and embryo transfer or intracytoplasmic sperm injection, gestational age of 24-34 weeks and intact fetal membranes.
Exclusion criteria: Hypersensitivity to tocolytic drugs and established preterm labour cervical dilatation more than or equal to 4cm.
For every patient the following was done: Full detailed history, medical history was taken from each patient including) special emphasis on medical and surgical history, history of general disease e.g., diabetes mellitus ( , Examination: General including (blood pressure, pulse, temperature and respiratory rate and obstetrical examination), Investigations including: Obstetric ultrasound to detect any obstetric disorder, Measurement of cervical canal length, Measurement of uterocervical angle (UCA).
Summary
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Results of the current study could be summarized as follow:
• There was no statistically significant difference between patient and control groups regarding age (P=.0648). while there were high statistically significant differences regarding BMI, Gestational Age, Parity and Gravity (P<0.001).
• There were high statistically significant differences between patient and control groups regarding history of preterm labor, history of abortion and history of having low birth weight baby (P<0.001).
• There were high statistically significant differences between patient and control groups regarding Cervical Length, Uterocervical Angle and Gestational age at delivery (P<0.001).
• There was statistically significant association between Cervical length and parity, history of abortion, Gravity, BMI, History of preterm labor, Gestational age of delivery, Uterocervical angle (P<0.05).
• There was statistically significant association between Uterocervical angle and age, parity, Gravity, BMI, History of preterm labor, history of abortion, Gestational age of delivery, Cervical length (P<0.05).
• The sensitivity and the specificity of cervical length in prediction of preterm labour was 87% and 100%, respectively, at cutoff value of ≥34.5 and (p=0.018). while, the sensitivity and the specificity of uterocervical angle for predicting of preterm labour was 90% and 100%, respectively, at cutoff value of ≥72.5 and (p<0.001).