الفهرس 
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Abstract
SUMMARYUMMARY UMMARY
evere burns require appropriate fluid management in the acute phase. A massive volume of intravenous fluid is usually required to ensure adequate end-organ perfusion. Also, reactive oxygen species contribute to increased endothelial permeability.
Vitamin C, or ascorbic acid, is an inexpensive and readily available antioxidant commonly deployed in the clinical settings.
Several preclinical studies and two clinical studies demonstrated that high-dose vitamin C can reduce fluid infusion and subsequent edema.
The aim of this study was to detect the efficacy of intravenous vitamin C and plasma albumin level in burnt rats.
This study was an experimental study on 14 rats only not including any human and they were divided into two groups: group A that represented burnt rats that weren‘t injected with vitamin C and group B represented burnt rats that were injected with vitamin C.
Statistical analysis revealed the following:
1- There was no statistically significant difference found between two groups regarding albumin level and total proteins level before burn and Post burn 8h.
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Summary
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2- There was highly statistically significant difference between Albumin level and total proteins level before Burn, Post Burn 8h level and Post Burn 24h level in the red group that received vitamin C as well as the blue one that didn‘t receive vitamin C.
3- There was no statistically significant difference found between the two groups regarding the DROP of albumin and total proteins levels 8 h post burn.
4- It is concluded that vitamin C has no effect on burn resuscitation. This result may be due to the small study group as well as the two missed rats during the study and the short study duration. Multicenter trials are needed to fully characterize vitamin C impact in burn resuscitation to be done over longer duration and over larger study groups