الفهرس 
Caesarean sectionOnly 14 pages are availabe for public view
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Abstract
S
urgical site infections (SSIs) pose considerable morbidity and account for up to 20% of all nosocomial infections in surgical patients (Leaper, 2010). SSIs result in prolonged hospitalization and increase the probability of intensive care unit admission and readmission to the hospital with increased mortality (Engemann et al., 2003).
As a result, SSIs represent a substantial financial burden for both the patient and the health service (Urban, 2006). The SSIs-related actual cost may be even higher than estimated due to underreporting and the financial cost to society from disability payments, loss of tax revenue, and lost productivity (Chang et al., 2013).
Obesity is an independent risk factor for post-operative surgical site infection. The risk of post-cesarean surgical site infection has been shown to double for every 5 unit increase in body mass index (BMI) above 30 kg/m , occurring in about 10% of obese women undergoing caesarean section despite prophylactic strategies e.g. antibiotics (Hyldig et al., 2019).
Antibiotic prophylaxis has been a cornerstone in SSI prevention, and there is growing interest in the local delivery of antibiotics. Local delivery can potentially lead to a higher concentration of antibiotics within the target site while minimizing the risk of systemic toxicity (Chang et al., 2013).
This study aimed determine the efficacy & safety of irrigation of subcutaneous tissue by Gentamicin for caesarean section Incision in reducing the risk of post-caesarean wound complications among obese women compared with placebo.
Our results revealed that the rate of SSI was less in gentamycin (3%) (n=2/66) than control group (4.5%) (n=3/66) with no statistical significance between them
Our results revealed that the postoperative hospital stay and readmission rate due to SSI for the gentamycin group were also shorter but not statistically different in compared to the control group.
As evident from the current study, In obese women undergoing elective CS, wound irrigation with Gentamicin is not superior to wound irrigation with placebo (saline 0.9) regarding efficacy & safety.
Applying local gentamycin antibiotic irrigation during wound closure after cesarean section in obese patients is not recommended.
NO role of local gentamycin irrigation in subcutaneous tissue in prevention of wound surgical site infection.