الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
C
hronic obstructive pulmonary disease (COPD) is a disease state characterized by progressive airflow limitation, and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarettes smoking.
Chronic obstructive pulmonary disease (COPD) is common cause of morbidity and mortality worldwide. One third of patients detected using case finding approaches in primary care settings are asymptomatic or have mild symptoms.
Under diagnosis of COPD is serious problem in many countries world-wide because there are no generally detection tools available to detect high-risk patients for spirometry and patients will not go for COPD check-up until a serious issue happens like exacerbation.
The present study was cross sectional study conducted upon 112 subjects during the period from March 2019 to March 2020 who admitted to our Chest Department or visitED our outpatient clinics at Ain Shams University Hospitals.
The study population was subjected to:
1. Full detailed history including: age, sex, residency and full medical history with special emphasis on history of any chronic diseases, recurrent infections, current medications, duration of smoking and smoking index.
2. Thorough clinical examination.
3. Body Mass Index (weight/height2), was calculated by dividing weight in kilograms by height in meters squared. Height was measured to the nearest 0.5 cm using studiometer and body weight to the nearest 1 Kg while wearing light clothing and no shoes using a scale.
4. St George’s respiratory questionnaire
5. Spirometry with reversibility.
6. Complete blood count (CBC) with differential.
7. Chest X-ray.
8. Serum IL 5
9. COPD Assessment Test (CAT)
10. CRP
The results showed that the prevalence of eosinophilic COPD is 26.7% and eosinophilic COPD patients have higher BMI, more exacerbations rate, more duration of smoking and smoking index and higher level of IL-5.
And there is no significant relationship between the the eosinophilic and non eosinophilic patients as regards age, sex, CAT score.